|
KMID : 0605620180250010001
|
|
Journal of Korean Society of Biological Psychiatry
2018 Volume.25 No. 1 p.1 ~ p.8
|
|
|
The Roles of Frontal Cortex in Primary Insomnia : Findings from Functional Magnetic Resonance Imaging Studies
|
|
Kim Bo-Ri
Park Su-Hyun
Cho Han-Byul
Kim Jung-Yoon
|
|
|
Abstract
|
|
|
|
Insomnia is a common sleep-related symptom which occurs in many populations, however, the neural mechanism underlying insomnia is not yet known. The hyperarousal model explains the neural mechanism of insomnia to some extent, and the frontal cortex dysfunction has been known to be related to primary insomnia. In this review, we discuss studies that applied resting state and/or task-related functional magnetic resonance imaging to demonstrate the deficits/dysfunctions of functional activation and network in primary insomnia. Empirical evidence of the hyperarousal model and proposed relation between the frontal cortex and other brain regions in primary insomnia are examined. Reviewing these studies could provide critical insights regarding the pathophysiology, brain network and cerebral activation in insomnia and the development of novel methodologies for the diagnosis and treatment of insomnia.
|
|
|
KEYWORD
|
|
|
Sleep, Primary insomnia, fMRI, Frontal cortex, Functional connectivity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|